Turning African Health Data into Global Impact
At Xcene Research, we are pioneering a new paradigm of evidence generation in Africa because transforming healthcare requires more than innovation; it demands measurable impact. Positioned at the intersection of science, drug development, data analytics, and public health, our integrated data ecosystem connects real-world evidence to real-world outcomes, bridging research with practical, scalable healthcare solutions.
We partner with global sponsors, biotechnology innovators, academic institutions, and health systems to transform real-world data (RWD) into actionable insights that shape regulatory submissions, market-access strategies, pharmacovigilance, and public-health programs, both across Africa and worldwide.
As Africa’s healthcare landscape evolves rapidly with a growing burden of non-communicable diseases, increased investment in genomics and digital health, and a shift toward precision medicine, Xcene Research is leading the transformation. Our mission is to generate high-quality, ethically sourced, and globally aligned evidence that reflects the continent’s genetic diversity, disease burden, treatment pathways, and care environments.
Through this ecosystem, we are building Africa’s capacity not just to participate in global research, but to inform it, contributing to a future where African data drives global regulatory, clinical, and commercial decisions.
Our RWE Capabilities in Africa’s Emerging Markets
- Real-World Data Generation and Integration
We design and execute multi-country RWD programs across both public and private healthcare systems in Sub-Saharan Africa. Our network of hospitals, laboratories, and digital-health partners supports secure data capture across diverse populations. Data sources include electronic medical records (EMRs), disease registries, claims databases, biobanks, and mobile health platforms, aligned with global standards such as CDISC, OMOP, and HL7 FHIR for interoperability and analytics readiness. - Real-World Evidence Study Design and Execution
Our epidemiologists, statisticians, and clinical data scientists develop and implement RWE protocols tailored to the African context accounting for demographic variability, multi-morbidity, and diverse care settings.
We conduct:- Observational cohort and case-control studies
- Prospective and retrospective registries
- Comparative effectiveness research
- Drug utilization, adherence, and pharmacovigilance studies
- Pragmatic clinical trials leveraging digital patient tracking tools
- Health Economics and Market Access Integration
Our RWE data feeds directly into HEOR and HTA frameworks, supporting evidence-based pricing, reimbursement, and resource allocation. This enables governments and payers to make data-driven policy decisions and allows sponsors to demonstrate real-world value and clinical effectiveness for faster adoption and sustained access. - Advanced Analytics, AI, and Predictive Modeling
Xcene Research employs artificial intelligence (AI) and machine learning (ML) algorithms to mine large-scale healthcare datasets for predictive insights, outcome modeling, and early safety signal detection. Our advanced analytics pipeline supports real-world pharmacovigilance, risk–benefit assessment, and disease modeling across diverse populations bridging gaps between African health data and global regulatory needs. - Therapeutic Area Focus
Xcene’s RWE initiatives span high-priority therapeutic areas driving Africa’s disease burden and global research interest, including:- Sickle Cell Disease (SCD) – patient registries, gene therapy monitoring, newborn screening, and long-term outcomes tracking
- Oncology and Hematology – post-approval safety studies, biomarker analysis, and treatment pathway optimization
- Nephrology and Cardiovascular Diseases – RWE programs assessing chronic kidney disease (CKD) progression, hypertension, and diabetes management
- Infectious Diseases – including malaria, HIV, and emerging pathogens, with data supporting treatment effectiveness and antimicrobial resistance trends
- Women’s Health and Pediatrics – maternal and neonatal health outcomes, fertility treatments, and vaccine surveillance
These areas reflect our commitment to producing data that is both locally relevant and globally actionable, strengthening Africa’s contribution to global health innovation.
From Local Data to Global Evidence
Xcene Research connects African health data to global evidence networks by aligning with FDA RWE frameworks, EMA adaptive pathways, WHO digital health standards NAFDAC and regional regulatory frameworks. This allows our partners to leverage African datasets for global regulatory filings, market access dossiers, and health-technology assessments (HTA).
By standardizing data generation and governance, Xcene Research ensures that Africa’s RWE contributes meaningfully to global submissions, label expansions, safety monitoring, and precision-medicine research.
Through this approach, Xcene positions Africa as a data-generating hub of strategic value and not only for regional health decisions but also for global regulatory, reimbursement, and innovation pipelines.
Why Partner with Xcene Research
- Scientific Integrity: Our RWE programs are built on ICH-GCP, ISO, and WHO data-governance standards.
- Regional Depth: Active operations across 25+ African markets, supported by Xcene Laboratories and digital health networks.
- Global Alignment: Data outputs designed to support submissions to FDA, EMA, MHRA, NAFDAC and other regional authorities.
- Strategic Value: Real-world insights that enhance market authorization, pricing, reimbursement, and post-market surveillance decisions.
At Xcene Research, we don’t just collect data, we translate it into evidence that changes access, shapes policy, and advances global health equity.
